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Podcast: New Books In Public Health
Episode: Georg Striedter, "Model Systems in Biology: History, Philosophy, and Practical Concerns" (MIT Press, 2022)
Description: Biomedical research using various animal species and in vitro cellular systems has resulted in both major successes and translational failure. In Model Systems in Biology: History, Philosophy, and Practical Concerns (MIT Press, 2022), comparative neurobiologist Georg Striedter examines how biomedical researchers have used animal species and in vitro cellular systems to understand and develop treatments for human diseases ranging from cancer and polio to Alzheimer’s disease and schizophrenia. Although there have been some major successes, much of this “translational” research on model systems has failed to generalize to humans. Striedter explores the history of such research, focusing on the models us...