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Podcast: Decera Clinical Education Infectious Disease Podcast
Episode: Switching ART in a Virologically Suppressed Person With Suspected Underlying Resistance
Description: In this episode, Timothy J. Wilkin, MD, MPH, provides a case-based overview of switching antiretroviral therapy in a patient with viral suppression on their current regimen who has a history of virologic failure with drug-resistance mutations. Key findings from 2 relevant studies—the SWITCHMRK trial and Study 380-4030—are reviewed. The case discussion also highlights several other challenges that can be encountered in the switch setting, including incomplete immune recovery, comorbidities, and gastrointestinal intolerability of some antiretroviral drugs.Presenter:Timothy J. Wilkin, MD, MPH​Professor Medicine​Division of Infectious Diseases​Weill Medical College of Cornell...