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Podcast: Research To Practice | Oncology Videos
Episode: Melanoma | Oncology Today with Dr Neil Love: BRAF-Mutant Metastatic Melanoma
Description: Featuring an interview with Prof Axel Hauschild, including the following topics: Pan-tumor approval of dabrafenib/trametinib; data with adjuvant targeted therapy for melanoma (0:00) Emerging data with encorafenib/binimetinib for Stage II melanoma; switching from dabrafenib/trametinib to encorafenib/binimetinib (5:23) Recent data with ipilimumab/nivolumab versus dabrafenib/trametinib from the DREAMseq trial; using targeted therapy after immunotherapy (9:58) Relationship between tumor mutational burden and response to targeted therapies and immunotherapies; PD-L1 expression and efficacy of immunotherapy alone compared to in combination (15:36) T-cell targets for immunoregulatory antibody therapy; treatment for patients with underlying autoimmune disease (20:23) Influence of corticosteroids on immunotherapy efficacy; adver...