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Podcast: PeerView Clinical Pharmacology CME/CNE/CPE Video
Episode: Bernd Kasper, MD, PhD - On the Cusp of Change: Modernizing the Treatment of Desmoid Tumors With Novel Gamma Secretase Inhibitors
Description: Go online to PeerView.com/JST860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. The management of patients with desmoid tumors is currently transitioning from surgical approaches to more conservative strategies by utilizing systemic therapy. The discovery that desmoid tumors are almost universally associated with genetic alterations in the Wnt/β-catenin pathway has provided rationale for the development of gamma secretase inhibitors (GSIs), a new promising class of agents, and several are in late-phase testing. Although no systemic therapies have received regulatory approval for the treatment of desmoid tumors to date, it i...