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Podcast: Dr. Chapa’s OBGYN Clinical Pearls
Episode: Pravastatin For Preeclampsia: New (Feb 2023) Data (AJOG).
Description: The “cure” for preeclampsia is NOT delivery. Preeclampsia is an important signal for future cardiovascular complications once pregnancy is over. While there may not be a true “cure”, we do have options for chemoprophylaxis of preeclampsia. Currently, only low-dose aspirin is ACOG/SMFM endorsed for preeeclampsia prevention. But pravastatin is gaining steam. Pravastatin was previously classified (in the now discontinued FDA label) Category X. However, the FDA recently removed the warning regarding use of statins in pregnancy, resulting from the favorable data on pravastatin as a potential chemoprophylactic agent against preeclampsia. While short term fetal safety has already been documented, there wa...