Want to create an interactive transcript for this episode?
Podcast: Surfing the MASH Tsunami
Episode: S3 E46.3 - Discussing Clinical Trial Design at the NAFLD Summit
Description: The 2022 NAFLD Summit presented a range of perspectives and insights on fatty liver and metabolic diseases. In this conversation, the panelists explore issues around clinical trial design, focusing specifically on the value of Phases 2a and 2b and whether improvement in patient self-management during trials is a research artifact or a replication of reality. This conversation addresses two issues in clinical trial design. First, Roger Green draws on the Session 9 discussion of failed trials to ask which is the right way to proceed when a drug in a Phase 2b trial fails to reach its...