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Podcast: Surfing the MASH Tsunami
Episode: S3-E26.1 - Advancing NASH Best Practices In NITs: Quentin Anstee's Five Key Takeaways
Description: This conversation starts with Quentin Anstee sharing the five key takeaways for NITs in general and NIT Best Practices he developed while preparing recent talks for the Liver Forum and the ICFL meeting in Vienna:(1) As we have discussed on this podcast and elsewhere, trial endpoints around balloon hepatocytes are, in Quentin's words, "not sufficiently robust."(2) Rapidly attaining response from a given test (ALT, for example) is not necessarily a guarantee of early efficacy.(3) "Simple indirect biomarker panels like FIB-4" need to be interpreted with caution.(4) Since we do not have a single perfect...