Want to create an interactive transcript for this episode?
Podcast: Surfing the MASH Tsunami
Episode: S3-E14.4 - Ballooned Hepatocyte Analysis and Reassessing Drug Development
Description: One major discussion at NASH-TAG this year was about the inconsistency in ballooned hepatocyte identification and how this inconsistency inflates screen fail rates and possibly placebo response across studies. This conversation is part of a thorough exploration of this issue.This conversation starts with Roger Green wrapping up the earlier discussion of the relationship between holistic NASH assessment and ballooned hepatocyte scoring by saying it is not surprising that fibrosis is an element in ballooned cell scoring, given that pathologists start with a holistic assessment and work back from there.Jörn Schattenberg asks Quentin A...