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Podcast: Surfing the MASH Tsunami
Episode: S2-E52.3 - Can MRE Provide Reliable, Non-Invasive Clinical Trial Endpoints?
Description: Alina Allen and Stephen Harrison spearhead a discussion on how MRE results can provide a foundation for developing Subpart H Clinical Trial Endpoints from non-invasive testing data. Their comments stem from Alina's presentation of the recent Mayo Clinic paper, "MRE for Prediction of Long-Term Progression and Outcome in Chronic Liver Disease: A Retrospective Study." In this conversation, Alina summarizes the paper, after which Stephen Harrison asks questions about availability of subgroup analysis.Β For NASH to move "beyond the biopsy," researchers must develop reliable clinical trial endpoints using non-invasive tests. This conversation winds up centering around M...