Want to create an interactive transcript for this episode?
Podcast: CME
Episode: A Novel Therapeutic Approach in Myeloid Malignancies: Targeting the Neddylation Pathway
Description:
Host: Jennifer Caudle, DO
Guest: Mikkael A. Sekeres, MD, MS
Guest: Sara M. Tinsley, PhD, ARNP, AOCNP
Please note: This activity is no longer available for continuing education credit. There is a lack of available therapeutic options for the management of patients with myeloid malignancies, including myelodysplastic syndromes (MDS), chronic myelomonocytic leukemia (CMML), and acute myeloid leukemia (AML). Novel therapeutic approaches are being evaluated, particularly those that target the NEDD8-activating enzyme (NAE). Evaluating the rationale for NAE inhibition, assessing emerging safety and efficacy data on use of NAE inhibitors in myeloid malignancies, and...