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Podcast: UC San Diego (Video)
Episode: CARTA: Primate Skeletal Gene Regulation: Risks of Human Skeletal Disease Specifically Osteoarthritis with Genevieve Housman
Description: Phenotypic variation within the skeleton has biological, behavioral, and biomedical functional implications for individuals and species. Thus, it is critical to understand how genomic, environmental, and mediating regulatory factors combine and interact to drive skeletal trait development and evolution. One way to do this is by studying skeletal diseases that disrupt skeletal function — like osteoarthritis (OA) which is a chronic disorder characterized by the degradation of cartilage and underlying bone in joints and can lead to severe pain and mobility limitations. This talk will discuss what is known about OA in humans and other primates, as well as recent advances th...