Episode: Natural Killer Cell switching via demethylation of Histone 3 LYS may correlate with the human aging phenotypic hyper-inflammatory state. DJGPhD. 28.9.21
Description: Pro-inflammatory gene transcription is tanked when demethylation is inhibited but cytotoxicity of virally infected or cancer cells by NK’s (where demethylation is inhibited) remains intact.
References
J. Biol. Chem. 2018;293:2422-2437
J. of Biol. Chem. 2016. 291, 23756-23768
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