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Podcast: JAMA Clinical Reviews
Episode: Mendelian Randomization: How the Natural Assortment of Genes Can Mimic Randomized Clinical Trials
Description: The best evidence for proving cause-and-effect comes from randomized clinical trials. However, they are expensive and difficult to perform. The natural assortment of gene variants at birth can mimic randomization in some circumstances and yield important clinical information that can help physicians better care for their patients. Read the article: Mendelian Randomization Â