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Podcast: Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Episode: Grapefruit Juice Interactions
Description: On this episode of the podcast, I discuss my approach and strategies to handle grapefruit juice interactions.
Grapefruit juice causes drug interactions by inhibiting the CYP enzyme system. More specifically, it inhibits CYP3A4 which is responsible for the breakdown of many medications.
Quantity is always an important consideration when assessing grapefruit juice interactions. The more that is taken, typically, the more drug concentrations will be affected.
It is important to assess the use of grapefruit juice when your patient has a history of cardiovascular disease, cardiac conditions, pain, mental health disease, or...