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Podcast: ResusX:Podcast
Episode: Is ketamine safe for traumatic brain injury? A systematic review and meta-analysis
Description: For decades, a single dogma has ruled neurotrauma resuscitation: Never use ketamine in TBI. The historical fear that ketamine spikes intracranial pressure (ICP) has kept one of the most versatile, hemodynamically friendly induction agents on the shelf—but is that fear based on fact or outdated physiology?  Â
 In this episode, we dissect a massive 2026 systematic review and meta-analysis from the Journal of Critical Care .  By analyzing over 6,000 patients across 15 studies—including four RCTs and strictly post-2015 data—this paper puts the "old myth" to the ultimate test .  We break down how the researchers compared ketamine against other agents like p...