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Podcast: ResusX:Podcast
Episode: Efficacy and safety of anticoagulant therapy in sepsis: A systematic review and meta-analysis
Description: Sepsis and Coagulation: Is It Time to Put the Heparin Away?
Is "thinning the blood" the missing piece in the sepsis puzzle, or just a recipe for disaster? Sepsis triggers a deadly cascade of inflammation and clotting, yet the debate over therapeutic anticoagulation has left ICU clinicians caught between the potential for organ salvage and the perilous risk of hemorrhage. In this episode, we break down a 2026 systematic review and meta-analysis from the *Journal of International Medical Research*. The investigators pooled data from 10 major studies—including 8 randomized controlled trials—covering nearly 7,500 adult patients to determine if agents like...