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Podcast: JACC Specialty Journals
Episode: Polygenic risk for cardiometabolic and cardiovascular disease in a multi-ethnic cohort of breast cancer survivors | JACC: CardioOncology
Description: Polygenic risk scores showed associations with several cardiometabolic outcomes in breast cancer survivors but did not improve prediction beyond traditional clinical factors. Their performance varied across ancestry groups and was weakened in patients exposed to cardiotoxic therapies, highlighting limits of current genetic risk tools.