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Podcast: Mind & Matter
Episode: Synapse Energetics & Fat Metabolism in the Brain | Timothy Ryan | 241
Description: Send a textHow brain synapses work and fuel themselves with fat.Episode Summary: Dr. Timothy Ryan talks about the high energy costs of synapses, the role of mitochondria and glycolysis, and challenge the long-held view that the brain relies solely on glucose by discussing new evidence that neurons burn fats from lipid droplets for fuel, especially during activity. The talk touches on metabolic flexibility, links to epilepsy treatments like ketogenic diets, neurodegenerative diseases, and future research on brain energy sources.About the guest: Timothy Ryan, PhD is a...