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Mind & Matter

Whether food, drugs or ideas, what you consume influences who you become. Learn directly from the best scientists & thinkers alive today about how your mind-body reacts to what you feed it.The weekly M&M podcast features conversations with the most interesting scientists, thinkers, and technology entrepreneurs alive today.Not medical advice.At M&M, we are interested in trying to figure out how things work, not affirming our existing beliefs. We prefer consulting primary rather than secondary sources and independent rather than institutional voices. If we encounter uncomfortable truths or the evidence suggests unfashionable ideas may be valid, so...

Light, Hunger & Mitochondria: Non-Image Forming Effects of Sunlight | Alexis Cowan | 287

110 hours 46 mins; April 03, 2026

Sleep, Brain Fat & Oxidative Stress | Amita Sehgal | 286

69 hours 18 mins; March 29, 2026

Peptides for Tissue Repair: BPC-157, TB-500 & the "Wolverine Stack"

65 hours 56 mins; March 22, 2026

Obesity Resistance & Leanness | 284

60 hours 0 mins; March 13, 2026

Mitochondria Genetics & Human Metabolic Variation in Health & Disease | Douglas Wallace | M&M 283

102 hours 11 mins; March 05, 2026

Bile Acids in Health & Metabolic Disease | Ep. 282

53 mins; February 28, 2026

Circadian Rhythms, Metabolism & Why Timing Your Meals Matters | Dr. Joseph Bass | 281

91 hours 3 mins; February 23, 2026

Opioid Addiction: RNA Biology, Brain Inflammation & Psychedelic Therapy | Ep 280

77 hours 54 mins; February 19, 2026

Estrogen & Body Fat: Menopause, Puberty, Females vs. Males | 279

99 hours 57 mins; February 14, 2026

The Claustrum: Cognition, Consciousness, Alcohol & Psychedelics | 278

95 hours 47 mins; February 09, 2026

Psychedelic Neurobiology: Sex-Specific Effects of MDMA & Psilocybin in Addiction & Reward Behavior | 277

70 hours 47 mins; February 04, 2026

AMPK: Biochemistry of Nutrient Sensing, Fasting, Cell Repair & Growth | Greg Steinberg | Ep. 276

80 hours 14 mins; January 25, 2026

Farm Food: Soy in Animal Feed, Pesticides, Phytoestrogens, Seed Oils & Regenerative Farming | Ep 275

96 hours 10 mins; January 19, 2026

Personalized Nutrition: Individual Responses to Foods, Fiber, Fats & Maternal Health | 274

80 hours 59 mins; January 14, 2026

Nutrition Content of Animal & Plant Foods: Beef, Plant-Based Meat, Raw vs. Processed Milk | Stephan Van Vliet | 273

96 hours 15 mins; January 09, 2026

Obesogens & Oxidative Stress in Metabolic Health, Neurodegeneration & Alzheimer's Disease | Robert Lustig | 272

131 hours 13 mins; January 04, 2026

Carbohydrates vs Ketosis in Exercise, Fatigue & Sports Science | Andrew Koutnik | 271

130 hours 26 mins; January 02, 2026

Stress & Psilocybin: Effects on Maternal Care & Offspring Development | Danielle Stolzenberg | 270

111 hours 57 mins; December 26, 2025

Soybean Oil: Obesity, Fatty Liver Disease, Gut Health, IBS & Colitis | Ep. 269

110 hours 3 mins; December 21, 2025

Dietary Fat & Light Regulation of Circadian Biology | Louis Ptacek | 268

84 hours 40 mins; December 17, 2025

Ketosis & BHB: Metabolic Diet Therapies, Brain Cancer & Exercise | Dominic D'Agostino | 267

101 hours 25 mins; December 12, 2025

Seed Oils, Chronic Inflammation, Heart Health & Marijuana | Ganesh Halade | 266

90 hours 54 mins; December 07, 2025

Evaluating Science: Clinical Trials, Epidemiology, Preclinical Studies & Mendelian Randomization | George Davey Smith | 265

86 hours 16 mins; December 02, 2025

Energy Metabolism & Information Processing in the Brain | Luis Felipe Barros | 264

83 hours 57 mins; November 26, 2025

How & Why Mitochondria Make Their Own Fat | Sara Nowinski | 263

57 mins; November 18, 2025

Hormones & Instincts: Hunger, Aggression & Parenting Behavior | Jonny Kohl | 262

60 hours 0 mins; November 07, 2025

Mitochondrial Transfer, Obesity & Immune-Metabolism Interactions | Jon Brestoff | 261

56 mins; November 02, 2025

Energy Resistance Principle in Life, Healing & Disease | Martin Picard & Nirosha Murugan | Ep. 260

129 hours 30 mins; October 28, 2025

Menstrual & Lunar Cycle Synchrony, Circadian Rhythms | Charlotte Förster | 259

57 mins; October 19, 2025

Evolution of Bipedality, Human Pelvis, Muscle & Brain | Terence Capellini | 258

82 hours 18 mins; October 15, 2025

Sleep, Mitochondrial Metabolism & Oxidative Stress | Gero Miesenbock | Ep. 257

77 hours 28 mins; October 10, 2025

Bacterial Infection, Oral Hygiene, Atherosclerosis & Heart Disease | Pekka Karhunen | 256

39 mins; October 05, 2025

Unlocking Energy: How Nutrition & Drugs Impact Your Mitochondria | Chris Masterjohn | Ep. 255

126 hours 15 mins; September 30, 2025

How Genes & Environment Shape Your Brain: ApoE, Alzheimer's & Space Radiation | Jacob Raber | 254

53 mins; September 26, 2025

Maternal Obesity, Immune System, Fatty Liver Disease & Epigenetics | Elvira Mass | 253

73 hours 5 mins; September 21, 2025

Scarring, Fibrosis, Oxidative Stress, and Psilocybin & Aging | Louise Hecker | 252

59 mins; September 16, 2025

Protein Restriction & Liver Hormones: Appetite, Brain, Behavior | Chris Morrison | 251

100 hours 18 mins; September 12, 2025

Cognition, Form, Regeneration & Metaphysics: Does Biology Arise From Math? | Michael Levin | 250

68 hours 34 mins; September 07, 2025

Fructose, Microglia, Anxiety & Brain Development | Justin Perry | 249

99 hours 43 mins; September 03, 2025

Autism, Acetaminophen (Tylenol) & Oxidative Stress | William Parker | Ep 248

101 hours 49 mins; August 29, 2025

Cholesterol: Immune Benefits, Heart Health, Statins & Research Malpractice | Uffe Ravnskov | 247

55 mins; August 25, 2025

Appendix, Gut Worms, Allergies & Autoimmunity | William Parker | 246

79 hours 56 mins; August 18, 2025

Cannabinoid System: Metabolism, Evolution & Energy Storage | Giovanni Marsicano | 245

104 hours 55 mins; August 13, 2025

Seed Oils & Heart Disease: Oxidized LDL, Cholesterol, Fat & Cardiology | Tucker Goodrich | 244

99 hours 25 mins; August 07, 2025

Evolution & Variation in Human Diet, Energy Expenditure & Metabolism | Herman Pontzer | 243

109 hours 42 mins; August 01, 2025

Sunlight: Cosmology, Energy Metabolism & the Physics of Life | Robert Fosbury | 242

133 hours 7 mins; July 27, 2025

Synapse Energetics & Fat Metabolism in the Brain | Timothy Ryan | 241

85 hours 59 mins; July 23, 2025

Microbiome as a Modifiable Organ System | Eugene Chang | 240

88 hours 12 mins; July 18, 2025

Sleep Duration, Sleep Timing & Short-Sleepers | Ying-Hui Fu | 239

54 mins; July 13, 2025

Hormones, Endocrine Disruptors & the Fate of Modern Liberal Society | Charles Cornish-Dale | 238

93 hours 58 mins; July 08, 2025

Circadian Biology: Genetics, Behavior, Metabolism, Light, Oxygen & Melatonin | Joseph Takahashi | 237

112 hours 33 mins; July 04, 2025

Cell Biology: Cytoskeleton, Self-Assembly & Self-Organization, Wound Healing | Bill Bement | 236

91 hours 14 mins; June 29, 2025

Computational Neuroscience, Machine Learning vs. Biological Learning, Large Language Models | Marius Pachitariu | 235

110 hours 4 mins; June 25, 2025

Brain Fat: Dietary PUFAs, Cannabinoids, Fatty Acid Binding Proteins, Anxiety & Mood | Steven Laviolette | 234

72 hours 53 mins; June 16, 2025

Feel the Burn: Seed Oils, Memes & Oxidative Stress | Brian Kerley | 233

130 hours 38 mins; June 11, 2025

SSRIs, Sexual Dysfunction, Suicide & Mass Shootings, How FDA Works | David Healy | 232

130 hours 9 mins; June 05, 2025

Psychedelic Chemistry, Magic Mushrooms, Kratom, Gray Market Research Chemicals, Vape Shops | Andrew Chadeayne | 231

98 hours 37 mins; May 25, 2025

Psilocybin & MDMA: Inflammation, Stress & Brain-Body Communication | Michael Wheeler | 230

69 hours 38 mins; May 20, 2025

Linoleic Acid, Seed Oils, mTOR & Breast Cancer | Nikos Koundouros & John Blenis | 229

107 hours 18 mins; May 15, 2025

Rhythms, Memory, Time, Place, Representation & the Brain | György Buzsáki | 228

108 hours 30 mins; May 10, 2025

Biophysics of Life: Biophotons, Light, Quantum Biology, Regeneration & Cancer | Nirosha Murugan | Ep. 227

99 hours 21 mins; May 05, 2025

Psychedelics & Cerebral Cortex: Neuroplasticity, Psilocybin, Ketamine | Alex Kwan | 226

77 hours 35 mins; May 01, 2025

Nutrition Epidemiology: Fake Science? | John Speakman | 225

65 hours 49 mins; April 26, 2025

Cancer Biology: Metabolism, Mitochondria & Energy | Thomas Seyfried | Ep. 224

112 hours 21 mins; April 23, 2025

Ketogenic Diet: Cholesterol, Plaque & Heart Heart | Matthew Budoff | 223

58 mins; April 19, 2025

Genetics & Neurobiology of Obesity: Hypothalamus, Leptin, Gut Hormones, Weight Loss Drugs | Giles Yeo | 222

93 hours 39 mins; April 15, 2025

Regenerative Energy & the Light Inside You | Jack Kruse | Ep 221

148 hours 0 mins; April 10, 2025

Cell Death, Oxidative Stress, PUFAs & Antioxidants | Pamela Maher | 220

100 hours 7 mins; April 08, 2025

Shamanism, Human Culture & the Evolution of Religion | Manvir Singh | 219

104 hours 18 mins; April 04, 2025

Chemical Exposures, Neurodegenerative Disease & Exposomics | Gary Miller | 218

93 hours 6 mins; March 31, 2025

Communication & Social Cognition in Elephants & Animals | Mickey Pardo | 217

99 hours 43 mins; March 27, 2025

Can Aspirin Prevent Cancer Metastasis? | Rahul Roychoudhuri | 216

86 hours 48 mins; March 23, 2025

Cancer Metabolism: Sugar, Fructose, Lipids & Fasting | Gary Patti | 215

105 hours 17 mins; March 19, 2025

Gut Microbiome Plasticity | Peter Turnbaugh | 214

41 mins; March 14, 2025

Causes of Diabetes: Insulin, Mitochondria, Genetics, Metabolism | Scott Soleimanpour | 213

49 mins; March 10, 2025

How Science Works: Meta-Research, Publishing, Reproducibility, Peer Review, Funding | John Ioannidis | 212

54 mins; March 05, 2025

Short-Chain Fatty Acids, Diabetes Subtypes & Wearable HealthTech | Michael Snyder | 211

50 mins; March 01, 2025

Public Health & Trust in Science in the Post-COVID Era | Martin Kulldorff | 210

38 mins; February 26, 2025

Thyroid Biology in Health & Aging | Diana van Heemst | 209

38 mins; February 14, 2025

Glyphosate, Choline & Alzheimer's: Toxins & Nutrition to Prevent Neurodegeneration | Ramon Velazquez | 208

42 mins; February 08, 2025

Glycosylation, CDGs & Role of Sugars Beyond Energy Production | Eva Morava | 207

48 mins; February 03, 2025

Cultural Evolution, Religion & the Origins of WEIRD Psychology | Joseph Henrich | 206

46 mins; January 29, 2025

Systems Biology, Personalized Medicine, AI & the Future of Health | Lee Hood | 205

58 mins; January 24, 2025

Preventive Medicine, Personalized Nutrition & Changing Your Microbiome | Momo Vuyisich | 204

52 mins; January 17, 2025

Metagenomics, Microbiome Transmission, Gut Microbiome in Health & Disease | Nicola Segata | 203

39 mins; January 12, 2025

🔒 Metagenomics, Microbiome Transmission, Gut Microbiome in Health & Disease | Nicola Segata | 203

81 hours 35 mins; January 06, 2025

🔒 Why Do Animals Sleep? | Vlad Vyazovskiy | 202

97 hours 23 mins; January 06, 2025

Why Do Animals Sleep? | Vlad Vyazovskiy | 202

50 mins; January 06, 2025

🔒 Aroma, Olfaction & Using AI to Digitize Smell | Alex Wiltschko | #201

97 hours 42 mins; December 30, 2024

Aroma, Olfaction & Using AI to Digitize Smell | Alex Wiltschko | 201

49 mins; December 22, 2024

Dietary Fats & Seed Oils in Inflammation, Colon Cancer & Chronic Disease | Tim Yeatman & Ganesh Halade | 200

53 mins; December 17, 2024

Ancient Diets, Human Carnivory, Mammoth Hunting, Clovis Culture & Origin of Native Americans | Ben Potter & Jim Chatters | 199

112 hours 55 mins; December 12, 2024

Vaccine Adverse Events & mRNA Biotechnology | Jessica Rose | 198

44 mins; December 07, 2024

Creation Myths, Stoned Apes & the Eve Theory of Consciousness | Andrew Cutler | 197

57 mins; December 04, 2024

Neurobiology of Stress: Resilience, HPA Axis, Stress Hormones, Sex Differences, Early Life | Rosemary Bagot | 191

40 mins; November 30, 2024

Mental Illness & Substance Abuse: Genetics, Psychosis, THC, Dopamine & the Brain | Jibran Khokhar | 190

100 hours 23 mins; November 26, 2024

Vaccine Contamination & Fiat Science | Kevin McKernan | 196

33 mins; November 21, 2024

Skin Biology: Hormones, Light, Vitamin D, Melatonin & Stress | Andrzej Slominski | 189

62 hours 58 mins; November 18, 2024

Psychedelics, Functional Neuroimaging & the Human Brain | Joshua Siegel | 188

71 hours 44 mins; November 13, 2024

Synesthesia & Effects of Digital Technology on Brain & Mental Health | Richard Cytowic | 187

68 hours 46 mins; November 10, 2024

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