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Authentic Biochemistry
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Membrane Biochemistry 68. Elevatum Hypostasis. Dr Daniel J. Guerra. 22.10.22b Authentic Biochemistry
29 mins; October 22, 2022
Membrane Biochemistry 67. VDAC oligimerization inhibition can block mitochondria-mediated apoptosis and NLRP3 inflammasome activation. DJGPhD.22.10.22.Authentic Biochemistry.
29 mins; October 22, 2022
Membrane Biochemistry 66. Staph aureus infection, autoimmune disease, biliary cholangitis, and neurodegeneration involve NLRP3 Inflammasome activation with core bioenergetic involvement. DJGPhD.
29 mins; October 20, 2022
Membrane Biochemistry 65. The integration of pro-inflammatory signaling from a plenum of molecular membranous events: The NRLP3 Inflammsome. DJGPhD. 19.10.22. Authentic Biochemistry.
29 mins; October 19, 2022
Membrane Biochemistry 64. Prelude to Biochemical Metaphysics and the Mitochondrial Membrane Damage Response I. Dr. Daniel J. Guerra.18.10.22.Authentic Biochemistry Podcast
29 mins; October 18, 2022
Membrane Biochemistry 63. The TCR:APC Chemokine receptor Trigger for Cytokine Stimulation. DJGPhD. 16 Oct 2022 Authentic Biochemistry Podcast
29 mins; October 16, 2022
Membrane Biochemistry 62. The T cell receptor mechanism II. Dr. Daniel J. Guerra. 14.10.22 Authentic Biochemistry
29 mins; October 14, 2022
Membrane Biochemistry 61. The Tcell membrane :APC synapse I. Dr Daniel J. Guerra 13.10.22 Authentic Biochemistry
29 mins; October 13, 2022
Membrane Biochemistry 60. Human neocortical membrane lipid evolution and the links to cognition,fasting, and neurodegeneration. Dr Daniel J. Guerra. 03Oct2022.Authentic Biochemistry.
29 mins; October 03, 2022
Membrane Biochemistry 59. Back to the Basics.Dr Daniel J. Guerra 30 September 2022.Authentic Biochemistry
29 mins; September 30, 2022
Membrane Biochemistry 58. Cardiolipin biosynthesis involves a PC-linoleic acid requiring maturase and a unique phosphatidylglycerol phosphate phosphatase. DJGPhD.25.9.22.Authentic Biochemistry
29 mins; September 25, 2022
Membrane Biochemistry 57. c-Fos osteoclastogenesis and control over acetyl ceramide mediated apoptosis.Dr Daniel J.Guerra.22.9.22 Authentic Biochemistry
27 mins; September 22, 2022
Membrane Biochemistry 56. Membrane Associated Cholesterol hydroxylation leads to bile acid conjugate- promoting human breast cancer stem cell proliferation. DJGPhD.19.9.22 Authentic Biochemistry.
29 mins; September 19, 2022
Membrane Biochemistry 55. A phosphoglycerolipid primer. Dr Daniel J. Guerra. Authentic Biochemistry Podcast. 16 Sept. 2022.
29 mins; September 16, 2022
Membrane Biochemistry 54. De-phospho TYR cFos doubles the VMax of specific glycolipid and phospholipid biosynthetic enzymes via ER stabilization.Dr Daniel J. Guerra. Authentic Biochemistry.14.9.22
30 mins; September 14, 2022
Membrane Biochemistry 53. cFos correlates with light-induced retinal membrane retailoring without de novo transcription. Dr Dan Guerra. 13.9.22.Authentic Biochemistry Podcast
29 mins; September 13, 2022
Membrane Biochemistry 52. Epigenetic modifications in pathophysiology and the synthesis of nascent membrane lipid in cell cycle progression. DJGPhD.12Sept22. AUthentic Biochemistry
29 mins; September 12, 2022
Membrane Biochemistry 51. The BRD4 epigenetic reader control over cardiac mitochondrial function via bioenergetic gene expression may be corrupted in oncogenic pharmacotherapy driven BETi. DJGPhD.
30 mins; September 08, 2022
Membrane Biochemistry L (50). SCFA's work via membrane free fatty acid receptors through transcription factor Nrf2 to reduce ROS with an epigenetic mark-up.DJGPhD.7Sept22.Authentic Biochemistry.
29 mins; September 07, 2022
Membrane Biochemistry 49. linking membrane reception and endocrine steroid lipid signaling to disease and longevity.DJGPhD.06Sept22
29 mins; September 06, 2022
Membrane Biochemistry 48.Coxsackievirus B enterovirus causes myocarditis in young men due to lack of estrogen-receptor-mediated control of mitochondrial fission/fusion & inflammation. DJGPhD.3Sept22
29 mins; September 03, 2022
Membrane Biochemistry 47. AMPK is regulated by steroid hormone activating kinases and calcium. DJGPhD. 02September2022, Authentic Biochemistry Podcast
29 mins; September 02, 2022
Membrane Biochemistry 46. Lung and endometrial cancer vs neurodegersative disease in steroid-sex-hormone NK cell biochemistry.DJGPhD.31.8.22. Authentic Biochemistry.
29 mins; August 31, 2022
Membrane Biochemistry XXXXV. Female NK Cytotoxicity due to Membrane Surface Receptors may Obtain Reduced Pathogen Infection Rates and Cancer in Women v. Men.DJGPhD.30.8.22 Authentic Biochemistry.
29 mins; August 30, 2022
Membrane Biochemistry 44. Synthesis of Lectures Video. Part One. Attached in show notes. Dr. Daniel J. Guerra. 29.8.22 Authentic biochemistry Podcast.
35 secs; August 29, 2022
Membrane Biochemistry 43. Action potentials and the mechanisms of electrochemical communication in biological systems. DJGPhD.26.8.22. Authentic Biochemistry
26 mins; August 26, 2022
Membrane Biochemistry XXXXII. Basic Electrobiochemistry of Biological Membranes. Dr Daniel J. Guerra. 24.8.22b Authentic Biochemistry Podcast Audio Lectures.
29 mins; August 24, 2022
membrane Biochemistry XXXXI. A priori Synthesis of Sex-linked Biochemical Dimorphism and Canonical Membrane Event Ontology. Dr. Daniel J. Guerra. 24.8.22.Authentic Biochemistry Podcast.
29 mins; August 24, 2022
Membrane Biochemistry XXXX. Immunological Response to Molecular Sex-linked Pattern Dimorphism Includes the Presentation of Differential Autoinflammatory Diseases. DJGPhD 22.8.22b.Authentic Biochem.
29 mins; August 22, 2022
Membrane Biochemistry XXXIX. Maternal Inheritance of Mitochondrial DNA and the Heterozygous XY Chromosomal Contributions to Sexually Dimorphic Biochemical Processes.DJGPhD.22.8.22. Authentic Biochem.
29 mins; August 22, 2022
Membrane Biochemistry XXXVIII. Sexual Biochemical Dimorphism Epigenetic Involvement in Early Infant CRF/HPA Axis and Subsequent Adult Neuropsychiatric Disease. DJGPhD.19.8.22. Authentic Biochemistry.
29 mins; August 19, 2022
Membrane Biochemistry XXXVII. CRF Receptor Studies in Pre-Clinical Research as Bootstrapped to Human MDD, GAD, PTSD and Addiction.DJGPhD.19.8.22. Authentic Biochemistry
29 mins; August 19, 2022
Membrane Biochemistry XXXVI. Sexual Differential CRF Signaling Accorded to Downstream Processing and Associated Neuropsychiatric and Phyiological Disorders.DJGPhD.17.8.22 Authentic Biochemistry.
29 mins; August 17, 2022
Membrane Biochemistry XXXV. Lipocortin-1 induces cortisol thus suppressing phospholipase A2, blocking eicosanoid and leukocyte inflammatory events. DJGPhD.16.8.22. Authentic Biochemistry
29 mins; August 16, 2022
Membrane Biochemistry XXXIV. Assymetric Glucocorticoid Pharmacotherapy in Rheumatoid Autoimmune Disease with T2Diabetes and the Fear Axis.DJGPhD.Authentic Biochemistry 15.8.22
29 mins; August 15, 2022
Membrane Biochemistry XXXIII> Are Oxytocin and Corticotropin Releasing Factor Antiinflammatory, Analgesic and Anxiolytic? Dr Daniel J. Guerra. 14.8.22. Authentic Biochemistry
29 mins; August 14, 2022
Membrane Biochemistry XXXII. The Subcortico-limbic network in Fear Conditioning as seen through the Dialectical Event Ontology lens. DJGPhD.10.AUG.22. Authentic Biochemistry
29 mins; August 10, 2022
Membrane Biochemistry XXXI. Corticotropin Releasing Factor and "Fear" Neurobiochemical Correlates in the CNS. Dr Daniel J. Guerra. 9Aug2022. Authentic Biochemistry Podcast
30 mins; August 09, 2022
Membrane Biochemistry XXX. Nociception as component of Subcortical-Limbic Involvement of the Conditioned Fear Response in Mammals. DJGPhD. 8Aug22. Authentic Biochemistry
29 mins; August 08, 2022
Membrane Biochemistry XXIX. Final discussions on serum albumin and membrane disruption mediated inflammatory modulation. Dr. Daniel J. Guerra. 7bAug22.Authentic Biochemistry.
29 mins; August 07, 2022
Membrane Biochemistry XXVIII. Serum Albumin as an arbiter of neuronal inflammation or peripheral removal of circulating endogenous Danger/Damage-Associated Molecular Patterns. 7Aug22. DJGPhD.
29 mins; August 07, 2022
Membrane Biochemistry XXVII. Traumatic Brain Injury and Ischaemic Stroke associated neuroinflammation is mediated through membrane caveolae. Dr Daniel J. Guerra.3Aug22. Authentic Biochemistry.
29 mins; August 03, 2022
Membrane Biochemistry XXVI. Lipid molecular structures and membrane morphology impacting biological activity. Dr Daniel J. Guerra. 01August2022. Authentic Biochemistry Podcast Productions.
29 mins; August 01, 2022
Membrane Biochemistry XXV. From Plotinus through Kant to Membrane lipids: an a priori synthesis of research scientific event concepts. DJGPhD.Authentic Biochemistry.31.7.22
60 hours 0 mins; July 31, 2022
Membrane Biochemistry XXIV. Legionella- assocated TLR mediated LPS containing sialic acid interactions and the Caveolar Involvement in Pathobiochemistry.DJGPhD. 29.7.22.Authentic Biochemistry.
29 mins; July 29, 2022
Membrane Biochemistry XXIII. DNA recombination and methylation associated autoimmune and cancer pathology via TLR4 and membrane lipid rafts. DJGPhD.28.7.22. Authentic Biochemistry
29 mins; July 28, 2022
Membrane Biochemistry XXII*. The dialectical event ontology of caveolae-associated disease is florid with no absolute relational, quantitative, qualitative or modal conformity.DJGPhD.27.7.22
29 mins; July 27, 2022
Membrane Biochemistry XX. Loss of CNS CA1-Caveolae Formation in Obese Type-2 Diabetics is Linked to insulin Resistance and Alzheimer's Disease. DJGPhD24.7.22. Authentic Biochemistry.
26 mins; July 24, 2022
Membrane Biochemistry XIX. Oxysterols and LDLR in atherosclerosis: transcriptional mediation of membrane control over cholesterol homeostasis. 21.7.22. DJGPhD.Authentic Biochemistry
29 mins; July 21, 2022
Membrane Biochemistry XVIII> Valproic acid and Platelt Activating Factor:Membrane lipids in Alzheimer's DiseaseDJGPhD 18.7.22 Authentic Biochemistry
29 mins; July 18, 2022
Membrane Biochemistry XVII. Epoigenetic changes in protein controlled membrane lipid transport in human disease. DJGPhD.14.7.22
29 mins; July 14, 2022
Membrane Biochemistry XVI. The Acid Sphingomyelinase Deficiencies. Dr Dan Guerra. 13.7.22 Authentic Biochemistry
29 mins; July 13, 2022
Membrane Biochemistry XV. REST mediated gene repression and membrane function and plaque formation in atherosclerosis. DJGPhD. 11JUly22. Authentic Biochemistry
59 mins; July 11, 2022
Membrane Biochemistry XIV. Apoptosis and Necroptosis review. Dr. Daniel J. Guerra. 8 July 2022. Authentic Biochemistry Podcast
26 mins; July 08, 2022
Membrane Biochemistry XIII.Fatty acid induced membrane protein phosphorylation can shift pro-oncogenic to apoptotic cell fate in human breast cancer cell lines. DJGPhD. 5July 2022 Authentic Biochem.
29 mins; July 05, 2022
Membrane Biochemistry XII. The specificity of membrane lipid raft molecular species and the dialectics of protein sorting. DJGPhD.3 July 2022 Authentic Biochemistry.
29 mins; July 03, 2022
Membrane Biochemistry XI. Inflammasomes and omega three fatty acid involvement in various pathogenic and human disease states. DJGPhD.02.July 2022.
30 mins; July 02, 2022
Membrane Biochemistry X. Dialectical Event Ontologies and the Complexity of Biological Systems. Dr. Daniel; J.Guerra 2 July 2022 Authentic Biochemistry
29 mins; July 02, 2022
Membrane Biochemistry IX. Omega Three fatty acid utilization via oxygenation to control inflammation. DJGPhD. 30.6.22 Authentic Biochemistry Podcast production
29 mins; June 30, 2022
Membrane Biochemistry VIII. The basics of lipid membranes. Part 1. Dr Daniel J. Guerra. Authentic Biochemistry Podacst Production. 28.6.22
29 mins; June 28, 2022
Membrane Biochemistry VII. DNA methylation and histone acetylation may be at the core of memory and learning via LTP associated Integral Membrane Excitation. DJGPhD.24.6.22 Authentic Biochemistry.
29 mins; June 24, 2022
Membrane Biochemistry VI. The involvement of membrane lipid omega 3 fatty acids in LTP and memory acquisition. Part 1. Dr Guerra. 23.6.22. Authentic Biochemistry
30 mins; June 23, 2022
Membrane Biochemistry V. Epigenetic alteration of gene expression is predicated by free will induced synaptic plasticity as an event ontology. DJGPhD. 21.6.22 Authentic Biochemistry
29 mins; June 21, 2022
Membrane Biochemistry IV. Synaptic Plasticity and Oncological Phenomena involving DNA Methylation. Dr. Daniel J. Guerra. 20.6.22 Authentic Biochemistry
29 mins; June 20, 2022
CytoEpigenetics XIX. Some examples of epigenetic methylation and acetylation patterns in disease and the concept of maintenance methylation. Dr Daniel J. Guerra. 06June2022
29 mins; June 06, 2022
CytoEpigenetics XVIII. Membrane lipid architectonics organized for cell cycle and both nuclear and mitochondrial biochemical mediation of gene expression. Dr. Dan Guerra. 05 June 2022
20 mins; June 05, 2022
CytoEpigenetics XVII. The role of ceramide metabolism in epigenetic and bioenergetic cross talk among multiple subcellular compartments. Dr Dan Guerra. 03June2022 Authentic Biochemistry Podcast
29 mins; June 03, 2022
CytoEpigenetics XVI. The Mt DNA replicase and helicase enzymes are epigenetically nuclear encoded and localize to the mitochondrial membrane into lipid rafts containing cholesterol. DJGPhD. 2June2022
29 mins; June 02, 2022
CytoEpigenetics XV.An AMPK phosphorylation cascade promoting mTOR pro-translational induction of NFkappa-B SASP transcription is modulated by NAD+ Sirtuin and PARP during Chromatin retailoring.DJGPhD
29 mins; May 27, 2022
CytoEpigenetics XIV. The details of AMPK mediated control over DNA methyl transferase thus coordinating bioenergetics with cell fate via the epitranscriptome. DJGPhD. 25.5.22
29 mins; May 25, 2022
CytoEpigeneticsXIII. Epitranscriptomics of Fatty acid Utilization is a driver of Heart-Failure associated Cardiorenal disease. Dr daniel J. Guerra. Authentic Biochemistry.22.5.22
29 mins; May 22, 2022
CytoEpigenetics XII. The central role of mitochondria in regulating cell fate and metabolic switching is necessary and universal in epigenetic modification of gene expression. DJGPhD.20.5.22
30 mins; May 20, 2022
CytoEpigenetics XI. The interactive intermediary metabolic architectonic of methylation and acetylation in epigenetic mediation of gene expression between the mitochondria and nucleus. DJGPhD.17.5.22
29 mins; May 17, 2022
CytoEpigenetics X. The IDH isofrom roles of mutant, hypoxic and constitutive activities mediate DNA, RNA and Histone3 Lys methylation patterns thus redirecting gene expression.DJGPhD.15.5.22
29 mins; May 15, 2022
Cytoepigenetics IX. c-MYC controls transcription of two dehydrogenases that alter the ratio of 2-HG/alphaKG thus controling epigenetic signatures on DNA and RNA in a cancer mouse model.DJGPhD.11May22
29 mins; May 11, 2022
CytoEpigenetics VIII. The epigenetic processors, TET and BRD4, mediate control over fatty acid oxidation, pyruvate metabolism, the electron tranport chain and OXPHOS. DJGPhD.8May22. Authentic Biochem
25 mins; May 08, 2022
Cytoepigenetics VIIB. Warburg glycolysis explained from an epigenetic perspective plus some details of DNA methylation/demethylation. DJGPhD. Authentic Biochemistry Podcast 06May2022
29 mins; May 06, 2022
Cytoepigenetics VIIa. Micro RNA control over the electron transport chain and oxidative phosphorylation via binding to nuclear and mitochondrial transcripts. DJGPhD03.may 2022. Authentic Biochemistry
21 mins; May 03, 2022
CytoEpigenetics V!. The 'magmatic' alteration of nuclear and mitochondrial gene expression via microRNA processing and translocalization is under bioenergetic control. DJGPhD. 2 May 2022.
29 mins; May 02, 2022
Cytoepigenetics V. Small interfering and micro RNA mediate mitochondrial and nuclear transcripts thus rendering cell fate, bioenergetics, and immunogenicity. DJGPhD.29.4.22. Authentic Biochemsitry
29 mins; April 29, 2022
Cytoepigenetics IV. Using Raman and IR spectroscopy to analyze the physical chemistry of pyrimidine nucleotide methylation. Dr. Daniel J. Guerra. 26.4.22. Authentic Biochemistry Podcast Productions
29 mins; April 26, 2022
Cytoepigenetics IIIB. The Geometrical constraints decribed by the valence shell electron pair repulsion in biochemical reactivity. DJGPhD.25.4.22
27 mins; April 25, 2022
Cytoepigenetics IIIA. Dissection of the PPAR-gamma epigenetic retailoring. Dr Daniel J. Guerra. Authentic Biochemistry Podcast. 25.4.2022
15 mins; April 25, 2022
Cytoepigenetics II. The First Principle of Biochemical Epigenetics and the dialectic of methylated promoter region PPAR-gamma and peroxisomal mitigation between rodent and human. DJGPhD.24.4.22
29 mins; April 24, 2022
CytoEpigenetics I. Introduction. Dr. Daniel J. Guerra . 22.4.22. Authentic Biochemistry Podcast Productions
29 mins; April 22, 2022
Authentic Biochemistry is moving to a remote geographical region but will do so seamlessly and with full dedication. Please SUBSCRIBE and take notice of the discussion I have recorded here. DJGPhD
29 mins; April 20, 2022
Diabetes XXXVI. Coda. Final lecture in diabetic dyslipidaemia.
29 mins; April 19, 2022
Diabetes XXXV. Rodent model adipose mitochondrial respiratory contribution to obesity control involves a selenium protein and UCP1 sulfenylation. Dr Daniel J. Guerra. Authentic Biochemistry.18.4.22
29 mins; April 18, 2022
Diabetes XXXIV. White vs brown adipocytes and the role of transcription factors and metabolic enzyme expression to mediate bioenergetics vs.lipogenesis in store depot fat.DJGPhD.17.4.22. Authentic B.
30 mins; April 17, 2022
Diabetes XXXIII. Synthesis of lecture arc Part 2. Dr Daniel J. Guerra. Authentic Biochemistry Podcast Studios. 16.4.22
29 mins; April 16, 2022
Diabetes XXXII. Fatty acid oxygenation and use of eicosanoid molecular species to regulate T2D-linked inflammation via the agonization of the nuclear receptor transcription factor PPAR.DJGPhD 15.4.22
29 mins; April 15, 2022
Diabetes XXXI. REDOX biochemistry mini-review and the roles of essential fatty acid elongation/desaturation metabolism and COX/LOX oxygenation as ligands for PPAR isoforms in T2D pharmacotherapy.
29 mins; April 14, 2022
Diabetes XXX. The pleitropic roles of free fatty acids and PPAR's as mediating insulin sensitivity, intermediary metabolism and the inflammatory response in T2D.Dr Daniel J. Guerra 13.4.22. Authentic
29 mins; April 13, 2022
DiabetesXXIX. THe CNS axis of Obesity-linked T2D via alterations in PPAR transcription factor mediated expression of ameliorative hippocampal AMPAR and LTP neural transmission in Alzheimer's Discsease
29 mins; April 12, 2022
Diabetes XXVIII. Diabetic nephropathy is a consequence of non-esterified free fatty acid associated ceramide induction of the IRS-1 phosphorylation in glomerular podocytes inducing inflammation
30 mins; April 08, 2022
Diabetes XXVII. Dyslipidaemia and the Insulin Resistance Axis. Dr. Daniel J. Guerra. Authentic Biochemistry Podcast 7April2022.
29 mins; April 07, 2022
Diabetes XXVI. Adipogenic and hypertrophic adiposity differentially control dyslipidaemia and Insulin resistance in association with pro-inflammatory cytokine induced T2D and breast cancer.DJGPhD.
29 mins; April 04, 2022
Diabetes XXIV. Sphingosine 1-phosphate targeting and the abalation of primary breast cancer metastasis: IL6 mediated tumorigenesis blockade? Dr Daniel J. Guerra 01April2022. Authentic Bbiochemistry
29 mins; April 01, 2022
Diabetes XXIII. Obesity-associated IL6 and sphingosine 1-phosphate are linked to breast cancer.Dr. Daniel J. Guerra. 31 March 2022. Authentic Biochemstry
29 mins; March 31, 2022
Diabetes XXII. Obesity and cancer are linked by inflammation and dyslipidaemia. Dr Daniel J. Guerra. 30.3.22 Authentic Biochemistry
29 mins; March 30, 2022
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