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Authentic Biochemistry
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Diabetes XXI. TAG accumulation in skeletal muscle of diabetics vs athletes and suggested role of Intramuscular TAG in Insulin Resistance due to subcelluar localization of lipid droplets. DJGPhD.27.3
29 mins; March 27, 2022
Diabetes XX. Intermediary metabolic allosteric regulation in the Myocardial Infarcted heart reveals HF aetiology from obesity-linked Type 2 Diabetes. DJGPhD.25.3.22. Authentic Biochemistry Production
29 mins; March 25, 2022
Diabetes XIX. THe ketogenesis bioenergetic system can be corrupted via DAG-kinase mediated pyroptosis in the obese/T2D CNS. Dr. Dan Guerra. 22.3.22. Authentic Biochemistry Podcast
29 mins; March 22, 2022
Diabetes XVIII. Myokine mediated muscle mass signaling is corrupted by obesity linked Type 2 diabetes via massive inflammation and dyslipidaemia.DJGPhD. 21.3.22. Authentic Biochemistry
29 mins; March 21, 2022
Diabetes XVII. Short and medium chain fatty acid derived ketones and skeletal muscle Myokines to improve cognitive and homeostatic well-being in humans. DJGPhD. 20.3.22 Authentic Biochemistry.
29 mins; March 20, 2022
Diabetes XVI. Fornix white matter fascicular region of the hippocampus nuclei is spared from neurodegeneration by dietary medium chain saturated fatty acid. DJGPhD.Authentic Biochemistry19.3.22
29 mins; March 19, 2022
Diabetes XIV. The Neuropsychiatric/Neurodegeneration axis from Sphingomyelin Degeneration to Increased Inflammation. Dr. Daniel J. Guerra. 17.3.22. Authentic Biochemistry Productions
29 mins; March 17, 2022
Diabetes XII. Free fatty acid dyslipidaemia associated dysregulation of hepatic and skeletal muscle Insulin Receptor Substrate (IRS)1/2 axis. Dr. Daniel J. Guerra15.3.22. Authentic Biochemistry .
29 mins; March 15, 2022
Diabetes XI. Biometrics in research interpretation. Dr Dan Guerra 14.3.22 Authentic Biochemistry.
29 mins; March 14, 2022
Diabetes IX. The role of peroxisomes in ether-linked lipid biosynthesis. Dr.Daniel J. Guerra. 07March2022. Authentic Biochemistry Podcast production
29 mins; March 07, 2022
DiabetesVIII. Subcellular organization and the role of lipid metabolism in mitochondria and peroxisomes. Dr Daniel J. Guerra. 05March22. Authentic Biochemistry
30 mins; March 05, 2022
Diabetes VII. Cholangiocarcinomas and the corruption of the biliary system as sequalae of obesity and associated pancreatic exocrine insufficiency of diabetes. Dr Dan Guerra. 3.March.2022. A.B.
29 mins; March 03, 2022
Diabetes V . PEI and Diabetic Dyslipidaemia with Primary Cholagiocarcinoma. Primer on lipid digestion and Lipoprotein Trafficking. Dr. Dan Guerra. Authentic Biochemistry 01.March.2022
30 mins; March 01, 2022
Diabetes IV. Pancreatic Exocrine Insufficiency in Types I, II, and III Diabetes Mellitus. Dr DAniel J. Guerra. 28.2.22. Authentic Biochemistry
29 mins; February 28, 2022
Diabetes III. Sphingosine 1-Phosphate in glioblastoma and prostagladin E2/EP4 in diabetic nephropathy-an axis of angiogenesis. Dr. Daniel J. Guerra. 25.2.22 Authentic Biochemistry
29 mins; February 25, 2022
Diabetes II. The Insulin resistance factor and glucose intoxication associated dyslipidaemia and introduction to diabetic nephropathy. DJGPhD. 23.2.22. Authentic Biochemistry Podcast.
29 mins; February 23, 2022
Type 2 Diabetes I. Initial lecture describing insulin resistance and dyslipidaemia. Dr Daniel J. Guerra 22.2.22 Authentic Biochemistry Podcast.
29 mins; February 22, 2022
Fatty Acids IX. The Monounsaturated fatty acid inhibition of ferroptosis and apoptosis leads to cancer progression. Pharmacotherapeutic Considerations. Dr Daniel J. Guerra. 17.2.22 Authentic Biochem.
30 mins; February 17, 2022
Fatty Acids VIII. The Potential for Ferroptosis enhancement via inhibition of Stearoyl CoA Desaturase as pharmacotherapy in Pancreatic Ductal Carcinoma.DJGPhD.16.2.22. Authentic Biochemistry.
29 mins; February 16, 2022
Fatty Acids VII. Stearoyl CoA Desaturase biochemistry and assocation with immune and metabolic disease. Dr Dan Guerra
29 mins; February 11, 2022
Fatty Acids VI. The Inflammasome paradigm and transcription factor-mediated cytokine production as result of high carbohydrate diet and obesity. Dr. Daniel J. Guerra. 10.Feb 2022. Authentic Bichem.
26 mins; February 10, 2022
Fatty Acids V. Ketogenesis as a therapeutic to redistribute preserved Heart Failure cardiac ejection fraction via blockage of mitochondrial protein hyperactylation. DJGPhD.9FEB22. Authentic Biochem.
29 mins; February 09, 2022
Fatty Acids IV. Adipocyte lipases and the Diacylglycerol PKC/PKD circuit of cellular degeneration leading to chronic inflammation-associated obesity. DJGPhD.07.Feb.22. Authentic Biochemistry
29 mins; February 07, 2022
Fatty Acids III. The inflammatory diseases and the correlation to dyslipidaemia. Dr Dan Guerra. 05 February 2022. Authentic Biochemistry Studios.
29 mins; February 05, 2022
Fatty Acids II. Obesity and lipotoxicity. Dr Daniel J. Guerra. Authentic Biochemistry 04. February 2022
29 mins; February 04, 2022
Fatty Acids I. Dr. Daniel J. Guerra. 03.02.22. Authentic Biochemistry Podcast
29 mins; February 03, 2022
Anabolism VII. The allosteric control of purine biosynthesis involves complementarity and recipricol maintenance of steady state ADP/GDP ratios. DJGPhD. 31.01.22. Authentic Biochemistry.
29 mins; January 31, 2022
Anabolism VI. de novo Purine Nucleotide Biosynthesis. Dr. Dan Guerra. 30.01.22. Authentic Biochemistry
29 mins; January 30, 2022
Anabolism V. The nucleic acids. Dr. Daniel J. Guerra. Authentic Biochemistry Podcast.28.01.22
29 mins; January 28, 2022
Anabolism IV. Cholesterologenesis. Dr Daniel J. Guerra. 26 January 2022. Authentic Biochemistry Podcast
30 mins; January 26, 2022
Anabolism III. Fatty acid synthesis de novo . Dr. Daniel J. Guerra. Authentic Biochemistry Podcast Productions. 25.01.22
29 mins; January 25, 2022
Anabolism II. The role of Acetyl CoA Carboxylase isoform expression and discrete allosteric regulation in controlling hepatic fatty acid metabolism. Dr Dan Guerra. 23.01.22. Authentic Biochemistry.
29 mins; January 23, 2022
Anabolism I. Dr Daniel J. Guerra Authentic Biochemistry Podcast Production 22.01.22
30 mins; January 22, 2022
Membrane lipid provide the architectonic signatures for cellular interactions including avirulence and either systemic and systematic-inflammatory disease. DJGPhD. 17.1.22. AuthenticBiochemistry
59 mins; January 17, 2022
Porphyria gingivalis derived dihydroceramides and serine dipeptide lipids secretion induce periodontitis and systemic hyperinflammation as associated with obesity and high sucrose diet. DJGPhD.16.1.22
29 mins; January 16, 2022
Dihydroceramides as virulence factors in periodontal disease. Dr. Daniel J. Guerra Authentic Biochemistry. 15 January 2022
29 mins; January 15, 2022
Pathogenesis and Virulence are Linked to Alterations in the Infection Court via Secretion of Bacteriocins in Dental Plaque-producing Caries and S. pneumoniae Migration to the Lower Respiratory Tract.
30 mins; January 13, 2022
Acquired Molecular Evolution of Antibacterial Resistance Unintentionally Selected via Pharmacotherapy to Counteract Natural Avirulence. DJGPhD. Authentic Biochemistry. 12.Jan2022
29 mins; January 12, 2022
Avirulence protein factor heterogeneity in multiple mammalian host/pathogen interactions. Dr. Dan Guerra. Authentic Biochemistry Production.11.Jan.2022
29 mins; January 11, 2022
Avirulence in the Streptococci and the Two-Component System of Histidine Kinase and Response Regulator. II. DJGPhD. Authentic Biochemistry 09Jan2022
29 mins; January 09, 2022
Avirulence and the mechanisms of pathobiochemistry I. Dr. Daniel J. Guerra. Authentic Biochemistry Podcast Production. 08.Jan 2022
29 mins; January 08, 2022
The neuronal porosomal and synaptosomal structural anatomy as a product of membrane lipid vesicular trafficking, Dr. Daniel J. Guerra Authentic Biochemistry. 05 January 2022
30 mins; January 05, 2022
The bioenergetic glucose sensing network of the appetitive reward pathway is linked to the periphery via the neuroendocrine system. DJGPhD. Authentic Biochemistry. 04.Jan.2022
29 mins; January 04, 2022
The Motor Neuron Association to Reward Pathway: Motor Neuron Disease , an Introduction. Dr. Daniel J. Guerra. 03 January 2022. Authentic Biochemistry Productions.
29 mins; January 03, 2022
The CNS and Pandemic Obesity: The Appetitive Reward Pathway, Energy Expenditure, and Neuroendocrine Signaling. DJGPhD. 02.Jan.2022 Authentic Biochemistry Productions.
30 mins; January 02, 2022
A short Pharmacology lecture on New Year's Day 2022. Dr Daniel J. Guerra. Authentic Biochemistry
29 mins; January 01, 2022
Appetitive Reward Pathway III.-Neurobiochemistry and Epigenetics of Addiction. DJGPhD. 31.12.21 Authentic Biochemistry
29 mins; December 31, 2021
Anhedonic and MDD- Associated Appetitive Reward Pathway Biochemistry and Pathophysiology II. DJGPhD. Authentic Biochemistry.30..12.21.
29 mins; December 30, 2021
Appetitive Reward Pathway Biochemistry and Neural Circuitry Regulation I. Dr. Daniel J. Guerra. 29.12.21. An Authentic Biochemistry Production.
30 mins; December 29, 2021
AMPK and Immuno-Epigenetic Biochemistry Part 2/2/ DJGPhD. Authentic Biochemistry 27.12.21
29 mins; December 27, 2021
AMPK and Immuno-Epigenetic Biochemistry Part 1. Dr. Daniel J. Guerra. 27.12.21. Authentic Biochemistry
29 mins; December 27, 2021
AMPK negatively regulates lipogenesis by phosphorylating ACCase 1&2 plus HMGCoA reductase thus supporting beta oxidation of fatty acids . Dr. Daniel J. Guerra. 22.12.21. Authentic Biochemistry
29 mins; December 22, 2021
AMPK is associated with the POMC vs, NPY neuronal axis under Leptin Control. DJGPhD. 20.12.21 Authentic Biochemistry
29 mins; December 20, 2021
AMPK Allosteric Regulation and Interaction with the Opposing mTORC Network. Part 2. Dr. Daniel J. Guerra. Authentic Biochemistry 19.12.21
30 mins; December 19, 2021
Bio-Molecular Regulator Series . AMPK. Part One. Dr. Daniel J. Guerra. Authentic Biochemistry Podcast Production.19.12.21.
30 mins; December 19, 2021
T-lymphocyte and macrophage membrane CD38 ecto-enzyme mediated NAD catabolism is associated with ageing and the decline in Sirtuin-mediated deacylase activity. DJGPhD.11.Dec.21' Authentic Biochemistry
29 mins; December 11, 2021
Aposteriori synthesis of neuroendocrine linked clock chronicity and the Senescent associated Secretory Phenotype through the synthetic apriori lens of NAD+. DJGPhD.10Dec21. Authentic Biochemistry
29 mins; December 10, 2021
How testosterone-aromatase derived estradiol transformation to 2-methoxy-17beta-estradiol can mitigate cell proliferation by promoting a senescent phenotype.DJGPhD. Authentic Biochemistry.8.DEC.21
30 mins; December 08, 2021
Blocking cellular senescence may suppress autoimmune diseases and reactive oxygen mediated cell death but non-ironically promote oncogenesis and tumor development during ageing. DJGPhD. 06.DEC.21
29 mins; December 06, 2021
Ageing and Asymmetric Dimethylarginine (ADMA)in Endothelial Nitric Oxide Synthase inhibition-associated decrease in respiratory vasodilation. Dr Dan Guerra 24.11.21 Authentic Biochemistry
29 mins; November 24, 2021
Closing the window and drawing the curtain: cancer phenotypes are resolute signatures of Immunosenescence and inflammaging induced epigenetic collapse of vital biochemical homeostasis. DJGPhD.20/11/21
29 mins; November 20, 2021
Sealing Fate: Immunosenescent and inflammatory mechanisms combine the ineffectual with the increscent pathophysiology of sickness unto death. DJGPhD. 17.11.21
29 mins; November 17, 2021
The interplay between Immunosenescence and inflammaging conduct the innate and acquired immune response toward functional cellular rigidity and incompetence obtaining morbidity and mortality. DJGPhD.
29 mins; November 13, 2021
Fine detail of Treg cell control over inflammation suppression via FoxP3 transcriptional modulation. Aging and Obesity will limit this control leading to hyperinflammation. DJGPhD. 08Nov2021
29 mins; November 08, 2021
T cell receptor signaling kinase dynamics after APC activation. Co-activating CD28 becomes deficient via immunosenescence thus corrupting T cell efficiency in the elderly. 26.10.2021 DJGPhD.
29 mins; October 26, 2021
Indeed oxysterol LDL , circulating hepatic-derived convertase, T lymphocyte differentiation and macrophage to foam cell degeneration obtain the aging cardiovascular/pulmonary pathophysiological state.
29 mins; October 22, 2021
How Oxysterol LDL associates with macrophage and T lymphocyte infiltration during aging to generate the hyperinflammatory atherosclerotic plaque. DJGPhD. 19.10.21. Authentic Biochemistry.
29 mins; October 19, 2021
Aging results in corruption of T lymphocyte differentiation associated with chromatin instability and epithelial to mesenchymal transitions leading to the pre-cancerous state. DJGPhD 16.10.21
29 mins; October 16, 2021
Lymphocyte maturation and the special Innate like Lymphocyte Subclass including Natural Killer and other ILC lineages. DJGPhD.14.10.21. Authentic Biochemistry
29 mins; October 14, 2021
Immunosenescence and Inflammaging via thymic Involution and comorbid pathophysiology of obesity and aging present a chronic inflammatory phenotype prone to morbidity. DJGPhD. Oct.04,2021. Authentic BC
30 mins; October 04, 2021
Natural cytotoxicity receptors (NCR's) within group 3 innate lymphoid cells (ILC3): an association of transcription factors in IBD's and aging. DJGPhD. 03.10.21 Authentic Biochemistry.
29 mins; October 03, 2021
Omega three fatty acids and PE N-methyl transferase are associated with methylation and acetylation patterning in NK cells via AMPK and stress.DJGPhD. 29 September 2021.
29 mins; September 29, 2021
Natural Killer Cell switching via demethylation of Histone 3 LYS may correlate with the human aging phenotypic hyper-inflammatory state. DJGPhD. 28.9.21
29 mins; September 28, 2021
The Genome and the Immunoepigenome interact across a three-way trigonal planar field with the Environment to Obtain the Aging Phenomena. DJGPhD.27.9.21
30 mins; September 27, 2021
Natural Killer cells and the epigenomics of gene expression: implications for the aging -senescent human. DJGPhD. 26 .9.21. Authentic Biochemistry
29 mins; September 26, 2021
REDOX Biochemistry Primer . DJGPhD Authentic Biochemistry . 24.9.21
28 mins; September 24, 2021
Video Lecture Announcement. Please Listen to this audio! Grazie, Dr. Daniel J. Guerra 22.9.21
5 mins; September 22, 2021
The Interferon I role in autoimmune disease and the corruption of mechanisms that lead to age-related morbidity and mortality.DJGPhD. 22.9.21
30 mins; September 22, 2021
The Aging Immune Response and Cellular Differentiation are characterized by Apoptosis vs. Necroptosis Mechanisms. DJGPhD. 20.9.21.Authentic Biochemistry Productions.
30 mins; September 20, 2021
Semaphorin works through mToR and thus the abl and AKT kinases in Macrophage reverse switching from lipogenesis to fatty acid oxidation. DJGPhD 18.9.21.
29 mins; September 18, 2021
Macrophage and T lymphocyte Inclusion to the Aging Human Pathobiochemical Phenotype. DJGPhD.Authentic Biochemistry 18.9.21
29 mins; September 18, 2021
Invitation to Watch my Youtube lecture I on the Aging Human Dialectic. Link found in the show notes. DJGPhD 16.9.21
2 mins; September 16, 2021
Membrane Biochemistry Primer and Introduction to Aging. Dr. Daniel J. Guerra. Authentic Biochemistry Productions. 13.9.21
29 mins; September 13, 2021
Summer Fades and Aging Advances through non-coding RNA's and the Immunological Axes. Dr Daniel J. Guerra. 9.9.2021 Authentic Biochemistry Productions.
29 mins; September 09, 2021
Hepatic Gluconeogenesis and Glycogen Metabolism: Canonical Allostery. Dr Dan Guerra. Authentic Biochemistry 07 Sept. 2021
29 mins; September 07, 2021
The hormonal and allosteric control over hepatic PFK2/FBPase2 via adenylate cyclase and Fructose 2,6 bis phosphate. DJGPhD.5Sept.2021. Authentic Biochemistry Productions.
30 mins; September 05, 2021
Glycerol 3-phosphate dehydrogenase mechanism and the finale of glycolysis. Authentic Biochemistry. Dr. Daniel J. Guerra 27.8.21
29 mins; August 27, 2021
Haemoglobin: Molecular Oxygen Binding Cooperativity and the role of 2,3 bis phosphoglyceric acid. DJGPhD 19.8.21
29 mins; August 19, 2021
A Necessary Interruption in Amino Acid Catabolism: Haemoglobin and Oxygen Transport Lecture I. DJGPhD. 11 August 2021
29 mins; August 11, 2021
Amino Acid Catabolism (Continued): Neurotransmitter and S-adenosyl MET interconversions. DJGPhD 09 Aug 2021
24 mins; August 09, 2021
Main Frame Amino Acid Degradation Pathways and Skeletal Muscle Performance and Ammonia Toxicity.02.Aug.2021. DJGPhD. Authentic Biochemistry
30 mins; August 02, 2021
The Urea Cycle and the endothelial ARGININE-Nitric Oxide Connection. DJGPhD 27.7.21.Authentic Biochemistry Podcast
29 mins; July 27, 2021
The Glutamate Dehydrogenase Axis Further Reveals the Role of Ischaemic Oxygen Availability for Neural Transmission in the Aging Brain. DJGPhD 20.7.21.
29 mins; July 20, 2021
The Glutamate Axis of Bioenergetics, Neurotransmission and Potential Contribution to the Aging Senescent Phenotype. DJGPhD 20.7.21
29 mins; July 20, 2021
Amino acid metabolism I: An initial primer for subsequent discussions in Aging. Dr Guerra. 07July2021. Authentic Biochemistry.
29 mins; July 12, 2021
Mesenchymal stem cell fate and the mediation of age-associated senescence or plasticity in the elderly via immune response valency. DJGPhD 03 July 2021
27 mins; July 03, 2021
Detailing the Senescent to Mesenchymal Transition in Aging : Links to Cancer vs. Apoptosis. DJGPhD 28 June 2021.
29 mins; June 28, 2021
Genomic damage, DDR, and the roles of inflammation and DNA epigenetic retailoring in the senescent phenotype. DJGPhD 24.6.21
29 mins; June 24, 2021
Pharmacodynamics: General Considerations and Clinical Trials. Dr. Dan Guerra. Authentic Biochemistry 12 June 2021
29 mins; June 12, 2021
Pharmacokinetics Synoptic with an Introduction to Aging Phenomena. Dr Daniel J. Guerra. 09June2021 authentic Biochemistry.
29 mins; June 09, 2021
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